Public-data research intelligence
Trial movement awareness without the enterprise contract.
See what moved on public trial records and FDA safety feeds. Each live card says whether it is a field diff or only a last-update.
Built for the gap below enterprise clinical intelligence
Enterprise life-sciences intelligence platforms are built for deep curated research, large teams, and annual procurement. Clinical Trial Signal serves the user who needs fast public-record awareness: what changed, where it changed, why it may matter, and where to verify it.
Enterprise platforms
Clinical Trial Signal
DataProprietary curated datasets
DataPublic-source monitoring
PricingAnnual contracts
PricingMonthly self-serve pricing
ScopeDeep pipeline / patent / regulatory / deal intelligence
ScopeDaily trial, safety, sponsor, literature, patent, and grant movement
Built forLarge-team workflows
Built forIndividual and small-team watchlists
Stack roleExpensive research stack
Stack roleSource-backed awareness layer
ClinicalTrials.gov
FDA MedWatch
openFDA recalls
EDGAR, patents, grants, and ex-U.S. registries are listed on the source map. They are not the free homepage feed.
Who this is for
Consultants
A brief a client can audit
What moved, the primary record, and the caveat. Not a curated pipeline database.
Small biotech and BD
Competitor timing without a contract
Watch Phase 2/3 industry programs and status reversals on a Monday morning email once you save a watchlist.
Specialist journalists
Public-record changes worth a call
Terminations, date slips, recalls, and FDA communications with a link to the source page.
What a signal looks like
Illustrative examples — not live records
Example signals. The cards below describe the shape of a signal from each source. Real signals on /trials, /safety, and /sponsors link directly to the primary public record.
Trial Movement
Example signal
Notable
Phase 3 GLP-1 obesity program — primary completion shifted
GLP-1 drug class · Phase 3 · Condition: Obesity
What changed. Registry record updated — primary completion moved later. Why it matters. Read-out timing shifts cascade through competitor positioning and analyst submission-timeline models.
Source type: ClinicalTrials.gov registry record
Fields surfaced: status, primary completion date, last update posted
FDA / Safety
Example signal
High Attention
openFDA Drug Enforcement — Class II recall posted
openFDA Drug Enforcement · Recall class: II · Multiple lots
What changed. A Class II recall covering multiple lots was entered into openFDA enforcement records. Why it matters. Class II indicates temporary or reversible health consequences are possible; supply chains and prescribers track these closely.
Source type: openFDA Drug Enforcement endpoint
Fields surfaced: classification, recall reason, lots, distribution pattern, status
Sponsor Disclosure
Example signal
Monitor
Public biotech sponsor — Form 8-K references FDA correspondence on Phase 2 program
SEC 8-K disclosure · Phase 2 oncology program · Sponsor-disclosed
What changed. A material-event filing reports receipt of FDA correspondence regarding the sponsor's Phase 2 program. Why it matters. Sponsor-disclosed FDA correspondence often precedes registry status changes by days to weeks.
Source type: SEC EDGAR Form 8-K filing
Fields surfaced: item, filing date, narrative excerpt with FDA-correspondence reference
Live trial movement
ClinicalTrials.gov · Last checked moments ago
Updated vs changed. A last-update date is not a field diff. Cards labeled Changed show previous and new values. Cards labeled Updated only have the current registry state.
Evidence Room
Every signal traces back to a primary public record
Every record we ship carries the same source-backed contract — the fields a researcher needs to verify, cite, and re-audit. If a field can't be filled from the primary record, the signal does not ship.
The source-backed contract
SourceNamed primary public source (e.g. ClinicalTrials.gov registry, openFDA enforcement, SEC 8-K)
Source URLDeep link to the specific primary record (NCT page, openFDA record, EDGAR filing)
Source timestampWhen the primary record reports the change
Ingested timestampWhen Clinical Trial Signal observed the change
Previous valueThe exact prior field value from the primary record
New valueThe exact new field value from the primary record
CaveatWhat the change does not establish (e.g. registry date moves do not establish cause; FAERS reports do not establish causation or incidence)
Evidence record
Example evidence record
Notable
Trial primary-completion change · Phase 3 GLP-1 obesity (illustrative)
SourceClinicalTrials.gov registry
Source URLDeep link to the live NCT record (shown on real signals)
Source published2026-05-30T00:00:00Z
Ingested2026-05-30T04:12:48Z
Previous valuePrimaryCompletion = 2026-12-15
New valuePrimaryCompletion = 2027-06-15
Normalized signaltrial.primary_completion_shift · delta = +6 months · severity = notable
AI-assisted interpretationA 6-month shift on a lead Phase 3 read-out moves the sponsor's regulatory submission window out of 2026, with downstream implications for competing-program timing and BD windows. Driver not disclosed in the registry record.
Registry date moves do not establish cause. Possible drivers include enrollment, supply, protocol amendments, analytical plan changes, or safety review. The sponsor has not publicly disclosed a reason in the registry record.
Why not enterprise platforms?
Clinical Trial Signal is not a proprietary curated enterprise database. It is a lower-cost public-record movement layer — built to detect what changed in public sources, generate source-backed briefs you can hand to a colleague or client, and tell you where deeper, paid-database research is actually worth the effort. Enterprise platforms still own deep curated pipeline / patent / regulatory / deal datasets; we sit beside them as an awareness layer, not a replacement.
Choose your tier
Match the tier to how you work
Pro · $199/mo
Independent analyst, consultant, journalist
Best for individual researchers who need fast, source-backed public-record awareness.
- Independent analysts and freelance researchers
- Healthcare and life-sciences consultants
- Journalists covering trials, FDA, or sponsor disclosure
- Academic and nonprofit researchers
Choose Pro
Analyst Desk · $399/mo
Biotech investor, BD, competitive intelligence
Adds SEC EDGAR, USPTO patents, NIH RePORTER, CMS Open Payments, and sponsor-comparison dashboards.
- Biotech and life-sciences investors
- Corporate and biotech business-development teams
- Competitive-intelligence and strategy functions
- Small biotech and emerging-pharma teams
Choose Analyst Desk
Research Team · $699/mo · 5 seats
Multi-seat research desk, pharma team, consultancy
Adds WHO VigiAccess, NICE, PMDA, disease-area dashboards, Evidence Room exports.
- Multi-seat sell-side and buy-side research desks
- Pharma medical-affairs, R&D strategy, and CI teams
- Consultancies serving multiple life-sciences clients
- Disease-foundation and policy research groups
Choose Research Team
Pricing
Free plus three paid tiers · subscribe any time · cancel any time
Free
$0
Search public registries, see today's surfaced signals, follow live FDA alerts and recalls.
Pro · $199/mo
$199/month
Full watchlists, daily refresh, source-backed briefs, PDF and CSV export.
Analyst Desk · $399/mo
$399/month
Adds SEC EDGAR, USPTO patents, NIH RePORTER, CMS Open Payments, and wire feeds.
Research Team · $699/mo
$699/month
Adds WHO VigiAccess, NICE, PMDA, disease-area dashboards, Evidence Room exports. 5 seats included.
Compliance-safe positioning. Clinical Trial Signal provides public-data research intelligence. It is not medical advice, legal advice, regulatory advice, investment advice, or a pharmacovigilance system of record. Public adverse-event data may be incomplete, duplicated, unverified, and cannot establish causation or incidence. Signals are intended for research screening and should be reviewed by qualified professionals.
Clinical Trial Signal